A PrEP user in New York City has become HIV positive with virus that is resistant to Truvada and other antiretroviral drugs, the HIV Research for Prevention (HIVR4P 2016) conference in Chicago heard today. This is only the second such case that has been reported, highlighting the rarity but not the impossibility of HIV infections in people who adhere to their PrEP (pre-exposure … [Read more...]
Change to recommended regimen for post-exposure prophylaxis (PEP)
Expert Advisory Group on AIDS Providing expert scientific advice on HIV Change to recommended regimen for post-exposure prophylaxis (PEP) EAGA was asked to review its recommended regimen for occupational post-exposure prophylaxis (PEP) in light of new evidence. When the PEP regimen was last changed, it was agreed that consistency should be maintained with the recommended … [Read more...]
Syphilis predicts HIV incidence among men and transgender women who have sex with men in a pre-exposure prophylaxis trial.
Background Syphilis infection may potentiate transmission of HIV. We sought to determine the extent to which HIV acquisition was associated with syphilis infection within an HIV pre-exposure prophylaxis trial (iPrEx) and whether Emtricitabine/Tenofovir (FTC/TDF) modified that association. Methods The Pre-exposure Prophylaxis Initiative (iPrEx) study randomly assigned 2499 … [Read more...]